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伊立替康体内代谢途径及代谢产物的研究进展 被引量:4

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摘要 目的综述伊立替康体内代谢途径和代谢产物的研究进展。方法检索国内外关于伊立替康及其代谢产物体内代谢途径的文献和资料,进行综述。结果和结论伊立替康具有非常复杂的体内代谢特征,在体内外受羧酸酯酶、葡萄糖醛酸转移酶、细胞色素P450和β-葡萄糖苷酸酶影响,代谢物之间可以相互转化,对于伊立替康的临床治疗有一定指导意义。
出处 《西北药学杂志》 CAS 2009年第6期515-517,共3页 Northwest Pharmaceutical Journal
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参考文献20

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共引文献44

同被引文献18

  • 1孙祥德,高革,齐伟,张金莲.高效液相色谱法测定血浆中伊立替康的含量[J].中国现代应用药学,2005,22(1):57-59. 被引量:7
  • 2刘凌翔,刘平.伊立替康治疗结直肠癌的耐药及其解救的研究进展[J].实用临床医药杂志,2005,9(11):38-41. 被引量:6
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