摘要
目的:对紫苏油乳剂进行皮肤急性毒性试验、皮肤刺激性试验及皮肤过敏性试验,以了解其安全性。方法:将紫苏油乳剂用于家兔背部完整或破损去毛区皮肤,观察其产生急性毒性和皮肤刺激性情况;采用致敏与激发接触紫苏油,观察豚鼠过敏情况。结果:紫苏油乳剂未产生明显皮肤刺激性;反复致敏后使用,也无皮肤与全身过敏反应。结论:紫苏油乳剂皮肤用药是安全的。
Objective： To determine the toxic effect of perilla volatile oil emulsions on skin. Method： The cutaneous irritation experiment was carrried out on the rabbit, and the skin allergic response experiment was carried out on health guinea pig. Result： No irritation of aciclovir gel on the integral or damaged skin of rabbit was observed. Sensitization effect on the skin of guinea pig was not found. Conclusion： Topical use of perilla volatile oil emulsions on the animal skin is safe.
出处
《中国药师》
CAS
2009年第11期1547-1548,共2页
China Pharmacist
