摘要
目的探讨单鼻孔入路垂体腺瘤手术前后是否应常规使用激素的问题。方法比较37例单鼻孔入路切除垂体腺瘤患者术前及术后1、3、7 d血清皮质醇浓度。结果术后第1、3 d与术前比较有统计学意义,第7 d与术前比较无统计学意义。除2例短期使用糖皮质激素替代治疗外,均未常规使用激素且疗效满意。随访2年无垂体功能低下表现。结论单鼻孔入路垂体腺瘤切除手术前后无常规使用激素的必要,是否使用激素应视临床症状及检验结果而定。
Objective To investigate whether or not the steroids should be routinely given to patients through transmononasal transsphenoid surgery pre-and postoperative. Methods Cortisol level in serum of 37 cases by transsphenoidsurgery were analysed statistically. Results There is statistical significances before and the first and third day except the 7th day after operation. Of 37 cases,2 were given short term cortisone replacement therapy. There is no hypopituitarism at the follow up of two years. Conclusions There is no indication of routinely use of cortisone perioperative for transsphenoid surgey.
出处
《临床神经外科杂志》
CAS
2009年第3期147-148,共2页
Journal of Clinical Neurosurgery
关键词
单鼻孔入路
垂体腺瘤
激素水平
transmononasal transsphenoidal approach
pituitary adenoma
cortisone