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HIV/AIDS患者免疫重建炎性综合征研究进展 被引量：2

Progresses in Studies on Immune Reconstitution Inflammatory Syndrome in HIV/AIDS Patients
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摘要 免疫重建炎性综合征发生于艾滋病患者应用高效抗反转录病毒疗法后的免疫重建过程中,本文分别对其概念、发病机制、诊断、临床表现和治疗等方面进行了综述。综合文献资料认为在病人的诊治上最重要的一点是提高对免疫重建炎性综合征的诊断和鉴别,以免延误病情。免疫重建的特征之一是恢复了针对机会性感染致病原的免疫反应,因此除非有可能威胁患者生命或导致高致残率外,都应继续应用高效抗反转录病毒疗法。 Immune reconstitution inflammatory syndrome （IRIS） occurred in the process of immune reconstitution disease after highly active antiretroviral therapy. In this paper, the concept, diagnostic criteria, clinical manifestations and treatment of IRIS were reviewed. It is important to improve diagnosis and differentiation of the IRIS and reduce delays. One of the characteristics of immune reconstitution is restoration of immune response to opportunistic infections. Therefore, unless there is a threat to patient＇s life or a risk that may lead to a very high rate of disability, the highly active antiretroviral therapy should be continued.
作者 吴巍 黄世敬 王阶
机构地区 中国中医科学院广安门医院免疫重建项目办公室
出处 《首都医科大学学报》 CAS 北大核心 2009年第5期710-713,共4页 Journal of Capital Medical University
基金 国家科技重大专项(2008ZX10005-004)资助项目~~
关键词 HIV/AIDS 高效抗反转录病毒疗法 免疫重建炎性综合征 HIV/AIDS highly active antiretroviral therapy immune reconstitution inflammatory syndrome
分类号 R512.91 [医药卫生—内科学]
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参考文献18

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共引文献36

同被引文献25

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引证文献2

二级引证文献2

首都医科大学学报
2009年 第5期

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