摘要
点击化学是2001年诺贝尔化学奖获得者美国化学家Sharpless提出的一种快速合成大量化合物的新方法。介绍了点击化学的概念及其主要反应类型,综述了点击化学作为一种新的合成方法在药物开发、聚合物合成和表面修饰等领域的应用,并对其发展前景进行了展望。
Click chemistry is a quick synthetic method brought up by American chemist Sharpless who won the Nobel Prize in chemistry 2001. In this paper, basic conceptions of click chemistry and main reaction types are introduced. As a new synthetic method, the application of click chemistry in drug discovery, polymer synthesis and surface modification is reviewed. Future developing trends of click chemistry is also prospected.
出处
《化学教育》
CAS
北大核心
2009年第10期3-5,共3页
Chinese Journal of Chemical Education
关键词
点击化学
药物开发
聚合物合成
表面修饰
环加成反应
click chemistry, drug discovery, polymer synthesis, surface modification, cycloaddition reaction