摘要
目的:探讨慢性湿疹患者治疗前后血清IL-2、IL-6和胃泌素(Gas)水平的变化及意义。方法:应用放射免疫分析对38例慢性湿疹患者进行治疗前后血清IL-2、IL-6和Gas检测,并与35名正常健康人作比较。结果:在治疗前血清IL-2水平非常显著地低于正常人组(P<0.01),而IL-6和Gas则显著地高于正常人组(P<0.01),经治疗1个月后,除IL-6、Gas水平与正常人组比较无显著性差异外(P>0.05),IL-2与正常人组比较仍有显著性差异(P<0.05)。结论:检测慢性湿疹患者血清IL-2、IL-6和Gas水平的变化对了解病情、指导临床实践有重要的临床价值。
Objective To explore the clinical significance of changes of serum IL-2,IL-6 and gastrin levels after treatment in patients with chronic eczema.Methods Serum IL-2,IL-6 and gastin were detected with RIA both before and after treatment in 38 patients with chronic eczema and 35 controls.Results Before treatment,serum IL-2 levels in the patients were significantly lower than those in the controls（P〈0.01）,while serum IL-6 and gastrin levels were significantly higher（P〈0.01）.After one month＇s treatment,the serum IL-6 and gastrin levels in the patients were no significantly different from those in controls（P〉0.05）,however,the IL-2 levels were still significantly lower than those in controls（P〉0.05）.Conclusion Serum IL-2,IL-6 and gastrin levels in the patients with chronic eczema were closely related to the severity of the diseases process and could be taken as indicator of treatment efficacy.
出处
《放射免疫学杂志》
CAS
2009年第5期462-464,共3页
Journal of Radioimmanology
