摘要
目的分析重度烧伤患者早期肾功能损害中胱抑素C(Cys-C)浓度的变化,探讨其临床意义。方法选取既往无肾病史烧伤患者87例,根据烧伤面积(BSA)分轻中度烧伤组、重度烧伤及时复苏组(4h内复苏)、重度烧伤延迟复苏组(>4h复苏)及40例体检健康人群作为对照组。分析入选对象血清中胱抑素C(Cys-C)、尿素氮(BUN)、肌酐(Cr)及尿微量白蛋白(MAL)的浓度,行统计学处理。结果轻中度烧伤组患者Cys-C、BUN、CR、MAL与对照组无统计学意义;重度烧伤及时复苏组血清Cys-C、MAL浓度高于对照组;重度烧伤延迟复苏组血清Cys-C的浓度较对照组与重度烧伤及时复苏组均有显著性增高;重度烧伤延迟复苏组血清Cys-C的浓度随着延迟复苏时间的延长而增高。结论重度烧伤患者血清Cys-C浓度与烧伤程度、复苏时间以及对肾脏的损伤程度呈正相关。
Objective To analyses the diversity of Cys-C in patients of severe burn whether cause prophase injury of kidney,and explore its clinical value. Methods According to burn surface area,87 patients without kidney disease divide into slight-moderate,timely or delayed resuscitation groups,40 persons by medical examination make as control group. We analyses the diversity of Cys-C,BUN,CR and MAL in patients of severe burn whether cause prophase injury of kidney by statistical way. Results Cys-C and MAL in severe burn timely resuscitation group were higher than those in control groups. Cys-C and MAL in severe burn delayed resuscitation group were higher than those in timely resuscitation group or control groups. With the time prolong,Cys-C had a significant higher in severe burn accompany delayed resuscitation group than those in timely resuscitation group or control groups. Conclusion Cys-C density in severe burn accompany delayed resuscitation group is concerned with the burn degree,resuscitative time and injury of kidney degree.
出处
《临床军医杂志》
CAS
2009年第5期815-817,共3页
Clinical Journal of Medical Officers
