摘要
目的:观察环磷腺苷葡胺治疗充血性心力衰竭(CHF)的临床疗效。方法:将160例CHF病人随机分为治疗组80例和对照组80例。对照组采用常规治疗,泊疗组在常规治疗基础上加用环磷腺苷葡胺120mg～180 mg,加入5%葡萄糖(或生理盐水)注射液250ml中静脉输注。每日1次,两组均以10天为1个疗程,1个疗程后观察疗效。结果:两组治疗后心功能较治疗前有明显好转,治疗组与对照组的总有效率分别为92.5%、73.8%(P<0.05),两组治疗后每搏输出量、射血分数、心排指数均较治疗前明显改善(P<0.01);治疗组与对照组治疗后比较每搏输出量、射血分数也有统计学意义(P<0.05)。结论:环磷腺苷葡胺能明显增强心力衰竭患者的左窒收缩功能和泵血功能,对CHF有良好的治疗效果。
Objective： To observe the clinical effects of meglumine Adenosine Cyctophosphate on Congestive heart failttre. Methods：By 160 patients with congestive heart failure were divided in two groups randomly：one treatment 80 patients and the other control 80 patients. The control group received the routine treatment and the MAC group were the routine treatment and intravenous injection of MAC,120mg-180mg into the percent 5 glucose（or physiology brine）250ml once daily, for ten days of one period of treatment,observing the effects after the one period of treatment. Results：The cardiac function of two groups were obvious improved after treatment than untreatment. The treatment group and the control group total effective respectively were 92.5%,73.8%（P〈0.05）. The two groups SV, EF and CI comparing untreatment were improved（P〈0.01）.The treatment group and the control group SV and EF were statistics meaning after treating（P〈0.05）. Conclusion： MAC can obvious improve the left systolic function of the heart and pump blood function, with the well effect for CHF.
出处
《中国医药导刊》
2009年第9期1501-1502,共2页
Chinese Journal of Medicinal Guide
关键词
充血性心力衰竭
环磷腺苷葡胺
Congestive heart failure
Meglumine adenosine cyclophosphate.
