摘要
目的探讨全肺放射治疗肺转移癌的心电图改变。方法选取1999-01—2007-12月收治48例进行全肺放射治疗的双肺多发肺转移癌患者的临床资料进行回顾分析。结果全组的心电图异常率占31．3％（15／48），其中窦性心动过速（〉100次／min）占12．5％（6／48），窦性心动过缓（〈60次／min）占8．3％（4／48），ST段改变（下移超过0．05mv）占8．3％（4／48），1例为完全性右束支阻滞占2．1％（1／48）。心电图异常出现时间分别在治疗第3周2例、第4周5例、结束时8例，随访至3个月后全部恢复正常。结论恶性肿瘤肺多发转移采用全肺放射治疗可获得较好疗效。照射面积大而放射剂量小可发生急性放射性心脏损伤，其损伤程度较轻且为一过性。
Objective To investigate electrocardiogram changes of the patients with metastases of lung cancer by radiatherapy. Methods From January 1999 to December 2007,48 patients of multiple pulmonary metastases in our hospital were treated by whole-lung radiation therapy. The clinical data of these patients were retrospectictively analyzed. Results The abnormal ECG rate was 31.3% （ 15/48）, in which sinus tachycardia （ 〉 100 beats / min） accounted for 12.5% （6 / 48）, sinus bradycardia （ 〈60 beats / min） accounted for8.3% （4 / 48）, ST segment changes （ST segment depression more than 0. 05my, ） accounted for 8.3% （ 4/48）, complete right bundle branch block accounted for 2.1% （ 1 / 48）. Abnormal ECG were appeared respectively in 2 cases at the time of the 3rd weeks, 5 cases at the 4th weeks in the treatment, 8 cases at the end of the treatment, All of the ECG resumed normal by follow-up for 3 months after the treatment. Conclusion Multiple pulmonary metastasis can be treated by whole lung radiation therapy available to good effect. Radiation of large area with less radioactive exposure dose can cause rapid cardiac injury, the injury is mild and transient.
出处
《中国临床新医学》
2009年第10期1021-1022,共2页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
基金
2007年江门市第二批科技计划项目[江科(2007)17号]
