期刊文献+

单中心62例无保护左主干病变支架植入的1年临床疗效 被引量:1

Following up one year clinical effect of 62 unprotecting left main coronary artery who received percutaneous coronary artery intervention in uni-center department of cardiology
下载PDF
导出
摘要 目的观察62例无保护左主干病变并行介入治疗的患者,分析其临床特点,随访1年临床疗效。方法非随机入选符合标准的患者,术前常规给予阿司匹林和氯吡格雷(波立维)治疗,术中根据病变分布、血管直径选择单支架和T支架、V支架、对吻(kissing)支架、挤压(crush)支架和裤裙(clotte)支架双支架术,6个月和1年时电话或门诊随访死亡、心肌梗死、靶血管血运重建和外科搭桥等不良心血管事件。结果病变分布开口、体部和末端分叉所占比例分别是24.2%、20.1%和54.8%,其中56.5%(35例)的患者使用单支架,43.5%(27例)的患者使用双支架。1年随访,猝死1例,急性心肌梗死2例,靶血管重建2例,冠状动脉搭桥(CABG)3例,1年总不良心血管事件发生率12.9%。结论无保护左主干病变患者行药物洗脱支架治疗临床疗效可靠,不良事件发生率与CABG相当,对其有选择性地行介入治疗安全可行。 Objective To observe 62 unprotecting left main coronary artery cases who received percutaneous coronary artery intervention(PCI) in the hospital for one year,and to analyze clinical characters. Methods Selecting 62 standards-compliant cases nonrandomly, before PCI, the patients took aspirin and plavix regularly, adopting one stent or two stent technique including T, V,kissing stent,crush and clotte modus operandi, following up death, acute maycadiac infarction,target vessel revasculariztion and coronary artery bypass bridge(CABG) at 6th month and 1 year from operation. Results The ratio of lesions in ostial,body and distal bifurcation was 24.2% ,21.0% and 54.8% ,altogether 56.5% (35 cases) patients receiving single stent,43.5% (27 cases) receiving two stents. At one year follow-up, death 1 case, acute maycardiac infarction(AMI) 2 cases, target vessel revasculariztion(TVR) 2 cases, CABG 3 cases, total major adverse cardiac events(MACE) was 12.9%. Conclusion The clinical effect is good in unprotectin left main coronary artery cases who received PCI,total MACE is not higher than CABG, and selectively adopting PCI in unprotectin left main coronary artery cases is suitable.
出处 《临床荟萃》 CAS 2009年第21期1849-1851,共3页 Clinical Focus
关键词 冠状动脉疾病 支架 治疗结果 随访研究 coronary disease stents treatment outcome follow-up study
  • 相关文献

参考文献4

二级参考文献37

  • 1张玉霄,卢才义,薛桥,刘鹏,颜伟,吴兴利,陈瑞.载雷帕霉素可降解聚合物涂层支架治疗冠心病的临床观察[J].中华心血管病杂志,2006,34(11):971-974. 被引量:19
  • 2Park SJ,Park SW,Lee JJ,et al.Long-term (three-year) outcomes after stenting of unprotected left main coronary artery stenosis in patients with normal left ventricular function[J].Am J Cardiol,2003,91:12-16.
  • 3Chieffo A,Stankovic G,Bonizzoni E,et al.Early and mid-term results of drug-eluting stent implantation in unprotected left main[J].Circulation,2005,111:791-795.
  • 4Valgimigli M,van Mieghem CA,Ong AT,et al.Short-and long-term clinical outcome after drug-eluting stent implantation for the percutaneous treatment of left main coronary artery disease:Insights from the rapamycin-eluting and taxus stent evaluated at rotterdam cardiology hospital registries (RESEARCH and T-SEARCH)[J].Circulation,2005,111:1383-1389.
  • 5Huang HW,Brent BN,Shaw RE.Trends in percutaneous versus surgical revascularization of unprotected left main coronary stenosis in the drug-eluting stent era:A report from the American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR)[J].Catheter Cardiovasc Interv,2006,68:867-872.
  • 6Kappetein AP,Dawkins KD,Mohr FW,et al.Current percutaneous coronary intervention and coronary artery bypass grafting practices for three-vessel and left main coronary artery disease.Insights from the SYNTAX run-in phase[J].Eur J Cardiothorac Surg,2006,29:486-491.
  • 7Smith SC,Feldman TE,Hirshfeld JW,et al.ACC/AHA/SCAI 2005 Guideline update for percutaneous coronary intervention:A report of the American College of Cardiology/American Heart Association task force on practice guidelines (ACC/AHA/SCAI writing committee to update the 2001 guidelines for percutaneous coronary intervention)[J].J Am Coll Cardiol,2006,47:e1-e121.
  • 8Silber S,Albertsson P,Aviles FF,et al.Guidelines for percutaneous coronary interventions.The task force for percutaneous coronary interventions of the European Society of Cardiology[J].Eur Heart J,2005,26:804-847.
  • 9Pfisterer M,Brunner-La Rocca HP,Buser PT,et al.Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents:An observational study of drug-eluting versus bare-metal stents[J].J Am Coll Cardiol,2006,48:2584-2591.
  • 10Nordmann AJ,Briel M,Bucher HC.Mortality in randomized controlled trialscomparing drug-eluting vs.bare metal stents in coronary artery disease:A meta-analysis[J].Eur Heart J,2006,27:2784-814.

共引文献19

同被引文献3

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部