摘要
目的:金冷法可通过低温和中药外用(透皮吸收)两种途径作用于睾丸。本研究目的旨在评价金冷法治疗少、弱精子症的疗效及安全性。方法:将符合纳入标准的39例少、弱精子症的男性不育患者用金冷内裤(金冷法)治疗,每天早、晚各1次,每次30 min,共3个月。观察治疗前后精液参数指标变化以及患者配偶的妊娠结局。结果:按要求完成治疗36例,其中31例精液质量有改善,总有效率为86.1%。少弱精子症组精子密度、前向运动精子百分率、精子活动率、精子总数、活动精子总数等精液参数指标在治疗后均有显著改善(P均<0.05),弱精子症组前向运动精子百分率、精子活动率、活动精子总数等精液参数指标在治疗后均有显著改善(P均<0.05)。治疗期间及治疗后随访2个月有5例配偶怀孕。治疗期间无明显不良反应发生。结论:金冷法治疗少、弱精子症具有疗效确切、使用方便、安全性好的特点,可作为男性少、弱精子症不育患者的一种新的治疗选择推广应用。
Objective： The Jinleng method is based on the principle of lowered temperature and diadermic action on the testis.The aim of this study is to investigate the effect and safety of the Jinleng method on oligospermia and asthenospermia. Methods： We treated 39 infertile males with oligospermia or asthenospermia with Jinleng underpants（Jinleng method） bid for 3 months,observed the changes in the sperm parameters of the patients after the treatment and recorded the pregnancy outcomes of their wives. Results： Of the 36 patients who accomplished the treatment,31 showed significantly improvement in semen volume,sperm concentration,forward sperm motility,total sperm motility,total sperm count and total motile sperm count（P 0.05）,with an effectiveness rate of 86.1%.Five of the patients wives achieved pregnancy in the 2-month follow-up.Adverse effects were found in none of the patients.Conclusion： Jinleng method is effective and safe for the treatment of infertile males with oligospermia and asthenospermia.
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2009年第10期952-955,共4页
National Journal of Andrology
关键词
男性不育
少精子症
弱精子症
金冷法
金冷内裤
male infertility
oligospermia
asthenospermia
Jinleng method
Jinleng underpants
