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早期骨关节炎的诊断和治疗研究进展 被引量：5

The clinical application advances in the diagnosis and treatmeant of early osteoarthritis
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摘要 骨关节炎(osteoarthritis,OA)是一种以关节软骨退行性变和新骨形成为特征的非炎症性疾病,是关节炎最常见的类型。本文回顾了与软骨代谢有关的标志物分子,以及聚蛋白多糖酶在OA软骨破坏中的作用,并就OA的早期诊断和治疗方面的研究进展做一论述。 Osteoarthritis（OA） is a degenerative joint disorder characterized by destruction and loss of articular cartilage as a result of an imbalance between catabolic and anabolic cartilage matrix metabolism.It is the most common form of arthritis.In this paper,we review the metabolic markers of OA,and the contribution of aggrecanase in OA.In addition,the early diagnosis and treatment of OA are discussed.
作者 李文 王广丽 张成琪 闫新峰
机构地区 山东省千佛山医院放射科 山东省千佛山医院骨关节中心
出处 《医学影像学杂志》 2009年第10期1344-1346,共3页 Journal of Medical Imaging
关键词 骨关节炎 聚蛋白多糖酶 代谢标记物 影像诊断 Osteoarthritis Aggrecanase Metabolic marker Imging diagnosis
分类号 R684 [医药卫生—骨科学] R445 [医药卫生—影像医学与核医学]
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参考文献10

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同被引文献26

  • 1唐福林,张奉春,郑文洁,李军,栗占国,苏茵,吴东海,马丽,周惠琼,黄烽,张江林,周乙雄,徐辉.双醋瑞因治疗膝骨关节炎的疗效与安全性多中心对照研究[J].中华风湿病学杂志,2005,9(7):421-424. 被引量：62
  • 2霍艳英,胡迎春,张开泰,李刚,吴德昌,许德凤,王莉,石毓君.非小细胞肺癌组织中Smad7表达谱的改变[J].中国药物与临床,2005,5(12):894-896. 被引量：2
  • 3杜宁,任峰,杨琦.膝关节骨关节病体征与功能的相互关系研究[J].中国中医骨伤科,1996,4(1):8-11. 被引量：4
  • 4张鹏,石关桐,郑昱新.膝骨关节炎滑膜细胞体外培养及生物学特性观察[J].中国骨伤,2006,19(11):656-658. 被引量：10
  • 5Michael J. O’Malley,Constance R. Chu,Stephen Kavic.Arthroscopic Optical Coherence Tomography in Diagnosis of Early Arthritis[J].Minimally Invasive Surgery.2011
  • 6Constance R.Chu,AshleyWilliams,DavidTolliver,C. KentKwoh,StephenBruno,James J.Irrgang.Clinical optical coherence tomography of early articular cartilage degeneration in patients with degenerative meniscal tears[J].Arthritis & Rheumatism.2010(5)
  • 7Nancy Simpson.Near-infrared diffuse optical tomography[J].Disease Markers.2002(5,6)
  • 8中药新药临床研究指导原则[M]. 中国医药科技出版社, 2002.中药新药临床研究指导原则[M]中国医药科技出版社,2002.
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  • 10Pelletier JP,Yaron M,Haraoui B,et al.Efficacy and Safety ofDiacerein in Os1teoarthritis of the Knee:a Double Blind,Placebo Controlled Trial The Diacerein Study Group. Arthritis and Rheumatism . 2000

引证文献5

二级引证文献23

医学影像学杂志
2009年 第10期

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