摘要
目的：为探索有效合理的综合治疗腹部外科危重症的方法，提出“四大一支持”综合疗法，并应用于临床，观察其疗效。方法：采用“四大一支持”综合疗法①短程大剂量山莨菪碱；②短程大剂量地塞米松；③大剂量抗需氧菌和抗厌氧菌抗生素联合正确应用；④大剂量应用腹腔灌洗液清洗腹腔；⑤一支持即完全的代谢营养支持。结果：75例危重外科病人并发多器官功能障碍24例，死亡10例，治愈65例。结论：“四大一支持”综合冲击疗法具有显著地改善微循环、抗细胞因子、抗氧自由基及促进损伤细胞逆转的作用。该方法对危重患者有扼止危重状态进展，促进症状缓解，改善微循环及良好的降温、抗毒、抗炎、抗休克作用，对重要脏器无损伤作用。
Application and evaluation of a new combined therapy of 'FHDOS' (four high dose and one support)to critical patients of abdominal surgery. Methods:75 critical patients with APACHEⅡ scoring 9～34,averaged 17.06±6.45 were treated with the new combined therapy. They included 24 cases of multiple organ dysfunction syndrome,41 cases of multiple traumas, 9 cases of acute suppurative cholangitis and 1 case of acute hemorrhagic necrotizing pancreatitis. The new combined therapy consists of ①high dose of anisodaminum in short-course; ②high dose of dexamethasone in short-course; ③high dose of efficacious antibiotics; ④thorough peritoneal lavage and; ⑤extensive nutritional and metabolic supports. Results: Among 75 cases treated, 24 were complicated by multiple organ dysfuncticn syndrome and 10 of them died. Conclusion: The new treatment can prevent the critical condition from deteriorating by improving microcirculation, inhibiting free oxygen radical formatin and promoting the recovery of injured cells. It is therefore effective in anti-shock and anti-inflammatory treatmea without any harmful effects.
出处
《急诊医学》
CSCD
1998年第6期393-395,共3页
关键词
山莨菪碱
四大一支持
综合疗法
急腹症
救治
Anisodaminum Dexamethasone Combined therapy of 'FHDOS' Abdominal surgery
