摘要
目的了解医院常用消毒剂对临床分离的鲍氏不动杆菌杀灭效果,探讨医院分离多药耐药鲍氏不动杆菌对医院常用消毒剂抗性。方法采用悬液定量杀菌试验进行了试验观察,数据采用spss13.0进行单样本t检验分析。结果用67 mg/L有效氯3、1 mg/L戊二醛、25 mg/L聚维酮碘作用15、min,对临床分离的多药耐药鲍氏不动杆菌和鲍氏不动杆菌标准菌种的杀灭效果差异有统计学意义,作用10 min杀灭效果差异无统计学意义;用250 mg/L有效氯1、25 mg/L戊二醛1、00 mg/L聚维酮碘作用1、5 min,对临床分离的多药耐药鲍氏不动杆菌和鲍氏不动杆菌杀灭效果差异有统计学意义,作用10 min杀灭率均能达到100%,差异无统计学意义。结论临床分离的多药耐药鲍氏不动杆菌对医院常用消毒剂有一定抗性;3种医院常用消毒剂按规定浓度对鲍氏不动杆菌临床分离株均具有良好的杀灭效果。
OBJECTIVE Our research＇s purpose is to find out bactericidal effect of common disinfectant to multidrug resistance Acinetobacter baumannii, and explore the resistance of multidrug resistance A. baumannii to common disinfectants. METHODS The research used Suspension quantitative bactericidal test as our experimental method. The data were analyzed by one-sample t-test in spss13.0. RESULTS Significant defference in bactericidal effect were found between multidrug resistance A. baurnannii and standard strains when using 67 mg/L effective chlorine, 31 mg/L glutaraldehyde, 25 mg/L Iodophor 1rain and 5rain. However, when time reach to 10 min, there was no difference. There were significant defference in bactericidal effect between multidrug resistance A. baumannii and standard strains when using 250 mg/L effective chlorine, 125 mg/L glutaraldehyde, 100 mg/L Iodophor 1min and 5rain. However, when time reach to 10 min, there were no difference. CONCLUSIONS Some multidrug resistance A. baumannii were resistant to common disinfectants. Three kinds of common disinfectants have excellent bactericidal effect to A. baumannii in provided concentration.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第21期2892-2894,共3页
Chinese Journal of Nosocomiology
基金
江西省科技厅支撑项目
关键词
消毒剂
多药耐药鲍氏不动杆菌
杀灭效果
Disinfectants
Multidrug resistance Acinetobacter baumannii
Bactericidal effect
