摘要
目的探讨边缘性癫(LE)和边缘性癫状态(LSE)的临床特点。方法回顾分析2例LE和1例LSE患者的临床资料。结果2例LE癫患者均为青年期发病,表现为发作性意识障碍、紧张、恐惧及各种形式的自动症和自主神经症状。脑电图呈现一侧或双侧颞区样放电。头颅MRI示1例左侧海马硬化,1例右颞叶内侧钙化灶。1例LSE患者系中年男性,表现发作性意识障碍、言行紊乱和精神症状,每次发作持续半小时以上;脑电图呈现双侧额叶、颞叶θ波或δ波;头颅MRI示:左颞叶前部蛛网膜囊肿。3例经用卡马西平或奥卡西平治疗发作得到控制。结论LE和LSE的临床特点是发作性自动症、自主神经和精神症状,与颞叶内侧海马及杏仁核损害有关。
Objective To investigate the clinical features of limbic epilepsies and limbic status epilepticus. Methods The clinical data of two patients with limbic epilepsies and one patient with limbic status epilepticus were analysed retrospectively. Results 2 patients with limbic epilepsia were all young-aged onset of the disease. They manifested bouts of unconsciousness, nervous and fear, various automatism and autonomic nerves symptom. EEG showed spike discharge in unilateral or bilateral temporal area. MRI showed left hippocampns sclerosis in one case. Another case presented calcification focus in right internal temporal. One patient with limbic status epilepticus was middle-aged male, he manifested repeatedly onset of unconscious insanity, behavior disorders and psychiatric symptoms. There was over 30 min for once onset. EEG showed 0 wave or 8 wave in bilateral frontal and temporal area. MRI showed arachnoid cyst in left temporal lobe anterior. Three cases were controlled by Carbamazepine or Oxcarbazepine. Conclusion The clinical feature of limbic epilepsies and limbic status epilepticus have bouts of automatism, automic nerve symptom and psychiatric symptom attact, which have relation to impairment of hippocampus and almond body in interal temporal.
出处
《临床神经病学杂志》
CAS
北大核心
2009年第5期381-383,共3页
Journal of Clinical Neurology
关键词
边缘性癫痫
边缘性癫状态
临床特点
limbic epilepsies
limbie status epilepticus
clinical features
