摘要
目的:了解和分析抗感染药物不良反应(ADR)发生的基本情况及其特点,为临床合理用药提供参考。方法:收集2008年抗感染药物引起的ADR资料,分别从患者年龄、给药途径、涉及药物种类及临床具体表现等方面进行统计、分析。结果:抗感染药物ADR中,女性患者较多(60.96%);静脉滴注给药引发的ADR最多(97.33%);抗感染药物引起的ADR临床表现又以皮肤及附件损害最多,其次是消化系统和神经系统。结论:临床应重视合理使用抗感染药物及其用药监测,以预防和减少ADR的发生。
Objective: To review and analyze the occurrence and characteristics of adverse reactions resulted from anti-infection drugs in our hospital and to provide references for the rational use of drugs in the clinic. Methods: ADR reports collected in our hospital caused by anti-infection drugs in 2008 year were analyzed statistically in terms of patients' age distribution, route of administration, drug varieties and the specific clinical manifestations. Results: Of the total cases induced by anti-infection drugs, most were female patients(60.96%); most of them were induced by ivgtt(97.33%). The most common clinical manifestations were the damage of skin and adnexa, digestive system and nervous adverse reaction. Conclusion: Rational use of anti-infection drugs and monitoring of the administration should be emphasized in clinic for the prevention and reduction of the occurrence of ADR.
出处
《中国医药导报》
CAS
2009年第33期108-109,共2页
China Medical Herald
关键词
抗感染药物
药物不良反应
用药监测
Anti-infection drugs
Adverse drug reaction
Monitoring of clinical drug use