摘要
艾滋病患者长期使用搞病毒药物可导致身体脂肪异常分布、血脂异常、糖代谢紊乱等,统称为脂肪代谢障碍综合征。这些代谢异常可能彼此联系,并增加了心血管疾病的发病率,因而正确处理这些代谢异常变得日益重要。此文对HIY感染者在HAART后的脂质代谢、形体改变与胰岛素抵抗等问题进行了综述。
Long-term treatment with antiretroviral agents in AIDS may be associated with abnormal fat redistribution, dyslipidemia and impaired glucose metabolism, collectively termed lipodystrophy syndrome. These metabolic abnormalities may be interrelated, and are associated with an accelerated risk of cardiovascular disease. Consequently, addressing these abnormalities has become increasingly important to the management of patients with HIV. In this article, the abnormal fat metabolism, body change and insulin resistance in the AIDS patients induced by HARRT are reviewed.
出处
《国际流行病学传染病学杂志》
CAS
2009年第5期331-333,共3页
International Journal of Epidemiology and Infectious Disease