摘要
瑞芬太尼是芬太尼家族中最年轻的成员。瑞芬太尼最吸引人的特性就是快速起效和作用快速消除,且不依赖输注时间的长短和任何器官的功能。因此,在要求快速起效或作用快速消除时,瑞芬太尼成为最佳选择。这样可以明显缩短插管和拔管时间。由于在停用瑞芬太尼后镇痛作用也很快消失。因此需要预先处理停用瑞芬太尼后的疼痛问题。
Remifentanil, one of the anilidopiperidine family, is probably the most original. Remifentanil has a unique pharmacokinetic profile that combines a short onset and the fastest elimination, independent of the infusion duration or any organ insufficiency. Consequently, it offers a unique titratability when its effects need to be quickly achieved or eliminated. This may permit both a significant reduction in weaning and extubation times. The absence of any residual analgesic effects after remifentanil-based anesthesia means that measures must be taken to prevent pain before the remifentanil infusion is discontinued.
出处
《实用疼痛学杂志》
2009年第5期388-391,共4页
Pain Clinic Journal
基金
湘南学院课题(项目编号08Y034)
关键词
疼痛
手术后
瑞芬太尼
镇痛
Pain, Postoperative
Remifentanil
Analgesia