摘要
目的探讨在G臂X射线机透视下经皮穿刺注射骨水泥诊治四肢骨转移癌的临床应用价值。方法18例四肢骨转移癌患者,其中男性11例,女性7例,年龄32～78岁,平均年龄57.4岁。临床影像学(X射线、CT或MRI)检查均提示四肢单发可疑骨转移病灶。临床伴有明显的病灶部位骨痛,均行经皮穿刺,先取病变组织行病理学检查,再注射骨水泥治疗。观察术后疗效、病理学检查阳性率和并发症。结果全部穿刺成功,术后疼痛症状均有明显缓解。组织活检16例为癌性浸润,2例为正常骨组织,阳性率为88.9%(16/18)。术中无严重并发症发生,术后随访3～6个月,平均随访4.5个月,病灶无扩大,无骨折发生。结论经皮注射骨水泥成形术诊治四肢骨转移癌临床疗效显著,是一种值得推荐的微创方法。
Objective To investigate the clinical effect percutaneous injection of polymethylmethacrylate under ＂G＂ armed fluoroscopy image on the management of limb bone metastasis. Methods A total of 18 patients with limb bone metastasis were enrolled, male 11, female 7, aged 32 - 78 years, mean age 57.4 years. The imaging characteristics（X-ray, CT or MRI） showed the single metastatic lesion in limbs. All the patients suffered from ostealgia with the lesion. After percutaneous biopsy and pathological examination, polymethylmethacrylate was injected into lesion. The treatment effects, positive rate of the pathological examination and clinical complications were observed. Results The success rate of percutaneous injection was 100 %, all patients had significant relief of pain symptoms. The biopsy results of 16 cases had cancer infiltrate, 2 cases were normal bone tissue. The positive rate of limb bone metastasis was 88.9 % （16/18 ）. No serious complications occurred after treatment. During the regular follow-up at 3 - 6 months（average follow-up 4.5 months）, it was showed all lesions without expansion, no fracture were found. Conclusion Percutaneous injection of polymethylmethacrylate has the remarkable clinical effect in treatment of limb bone metastasis. It is a minimally invasive approach worth to recommend.
出处
《生物医学工程与临床》
CAS
2009年第6期530-532,共3页
Biomedical Engineering and Clinical Medicine
关键词
四肢
骨转移癌
经皮注射骨水泥成形术
extremities
bone metastasis
percutaneous injection of polymethylmethacrylate
