摘要
目的探讨穴位埋线等不同干预方法对海洛因依赖大鼠CD4+、CD8+细胞百分数及CD4+/CD8+的影响。方法采用逐日递增法建立海洛因依赖大鼠模型,随机分为自然戒断组、美沙酮组、针刺组和穴位埋线组,给予相应干预结束后,比较各组大鼠外周血CD4+和CD8+细胞百分数、CD4+/CD8+的变化。结果美沙酮组CD4+、CD8+细胞百分数及CD4+/CD8+与自然戒断组比较,差异无统计学意义(P>0.05),针刺组和穴位埋线组CD4+、CD8+细胞百分数及CD4+/CD8+与自然戒断组比较,差异有统计学意义(P<0.05),针刺组和穴位埋线组CD4+、CD8+细胞百分数及CD4+/CD8+间差异亦有统计学意义(P<0.05)。结论穴位埋线能改善海洛因依赖大鼠紊乱的T淋巴细胞亚群,提高其细胞免疫功能。
Objective To explore the effect of different interventions on CD4^＋ , CD8^＋ , and the cell percentages of CD4^＋ , CD8^＋ in heroin dependence rats. Methods Heroin addiction rat models established by a daily ascending method were divided randomly into groups natural withdrawal （group A） , methadone （group B） , acupuncture （group C） and acupoint catgut embedding （ group D）. After corresponding interventions, the changes of peripheral blood CD4^＋ , CD8^＋ , and cell percentagesof CD4^＋ , CD^8＋ were compared between all groups. Results There was not significant difference in CD4^＋, CD8^＋ , and cell percentages of CD4^＋ , CD8^＋ between groups B and A （ P 〉 0, 05 ）, but groups C and D were significantly different from group A （ P 〈 0. 05 ）, and group C from group D （P 〈 0.05 ）. Conclusion Acupoint catgut embedding can improve disorders of T - lymphocyte subsets and increase their cellular immune function.
出处
《中国全科医学》
CAS
CSCD
北大核心
2009年第22期2074-2076,共3页
Chinese General Practice
关键词
埋线
针刺穴位
海洛因依赖
T淋巴细胞亚群
淋巴细胞计数
Embedding, thread
Acupuncture points
Heroin dependence
T - lymphocyte subpopulation
Lymphocyte count
