摘要
目的探讨癌抗原125(CA125)在尿毒症血透患者中的分泌情况及其临床意义。方法尿毒症血透患者416例,分别于血液透析前后静脉端采血标本检测CA125浓度,比较透析前后CA125浓度。按是否有浆膜腔积液分为无浆膜腔积液组和有浆膜腔积液组,分别比较血液透析前后CA125浓度。结果血液透析前后患者的CA125浓度差别无统计学意义;有浆膜腔积液组的CA125浓度在透析前、后均较无浆膜腔积液组明显升高。结论尿毒症伴有浆膜腔积液患者的CA125浓度明显升高,但该CA125浓度升高并非合并肿瘤所致,故不宜作为判断该类患者合并肿瘤的指标。
Objective To investigate the excretion of cancer antigen 125 in hemodialysis uremic patients, and to evaluate the clinical significance of CA125. Methods Four hundred and sixteen long- term hemodialysis patients were enrolled in this study. According to with or without serous cavity effusion, patients were classified into two groups. Venous CA125 concentration was compared between two groups and between before and after dialysis. Results Difference of CA125 concentration between before and after dialysis was no significant. Patients with serous cavity effusion show higher concentration of CA125,regardless of before and after dialysis. Conclusions The concentration of venous CA125 of uremic patients with serous cavity effusion was significantly higher than that of patients without serous cavity effusion. The higher concentration of CA125 was not used to prognoses cancer in uremic patients.
出处
《福建医科大学学报》
2009年第5期402-403,共2页
Journal of Fujian Medical University
基金
厦门市科技局指导性项目(3502z20077054)
