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重组人骨形态发生蛋白-7表达系统研究进展 被引量：4

Progress of Expression System of Recombinant Human Bone Morphogenetic Protein-7
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摘要 骨形态发生蛋白-7(BMP-7)在胚胎发育、肾脏保护、骨形成、代谢、再生等各个方面发挥着重要的作用,现已进入了临床应用阶段。我们简要综述了重组人BMP-7(rhBMP-7)的原核表达系统及真核表达系统,并对各表达系统的优缺点进行了分析。 Bone morphogenetic protein-7（BMP-7） plays important roles in fetal development, renoprotection, bone formation, bone metabolism, bone regeneration, and so on. It has been used clinically. In this article, the expression systems of recombinant human BMP-7 were introduced, including the bacterial expression system and eukaryotic expression system. Meanwhile, each system was compared with others in the merit and demerit.
作者 安新玲 韩金祥 王世立
机构地区 山东省医药生物技术研究中心
出处 《生物技术通讯》 CAS 2009年第6期846-848,873,共4页 Letters in Biotechnology
关键词 骨形态发生蛋白-7 大肠杆菌表达系统 毕赤酵母表达系统 CHO细胞表达系统 腺病毒 bone morphogenetic protein-7 bacterial expression system Pichia expression system CHO cells expression system adenovirus
分类号 Q78 [生物学—分子生物学]
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生物技术通讯
2009年 第6期

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