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快速眼动期睡眠行为障碍与神经变性疾病的研究进展 被引量：6

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摘要 快速眼动（rapid eye movement，REM）期睡眠行为障碍（REM behavior disorder，RBD）是以REM睡眠期肌肉弛缓现象消失并出现与梦境相关的复杂运动为特征的发作性疾病，可导致自伤及同床者受伤并使睡眠中断，既往认为RBD仅仅是一种独立的睡眠障碍疾病。最近几年研究显示，RBD与某些神经变性疾病如多系统萎缩、路易体痴呆、帕金森病、进行性核上性麻痹等关系密切。在路易体痴呆的新诊断标准中被列为疾病的重要特征之一，RBD可以在神经变性病之前数年出现，有可能是某些神经变性病的前驱症状，
作者 郝红琳 刘秀琴 黄颜 孙鹤阳 崔丽英 陈琳 孟琼
机构地区 中国医学科学院北京协和医院神经内科
出处 《中华神经科杂志》 CAS CSCD 北大核心 2009年第11期780-782,共3页 Chinese Journal of Neurology
关键词 快速眼动期睡眠行为障碍 神经变性疾病 进行性核上性麻痹 路易体痴呆 神经变性病 发作性疾病 多系统萎缩 RBD
分类号 R686 [医药卫生—骨科学]
  • 相关文献

参考文献20

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二级参考文献8

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共引文献10

同被引文献69

  • 1Iranzo A,Molinuevo JL,Santamaria J,et al.Rapid-eyemovement sleep behaviour disorder as an early marker for a neurodegenerative disorder:a descriptive study.Lancet Neurol,2006,5:572-577.
  • 2Boeve BF,Saper CB.REM sleep behavior disorder:a possible early marker for synucleinopathies.Neurology,2006,66:796-797.
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  • 8Iranzo A,Santamaria J,Rye DB,et al.Characteristics of idiopathic REM sleep behavior disorder and that associated with MSA and PD.Neurology,2005,65:247-252.
  • 9Gagnon JF,Bedard MA,Fantini ML,et al.REM sleep behavior disorder and REM sleep without atonia in Parkinson ' s disease.Neurology,2002,59:585-589.
  • 10Boeve BF,Silber MH,Ferman TJ.REM sleep behavior disorder in Parkinson' s disease and dementia with lewy bodies.J Geriatr Psychiatry Neurol,2004,17:146-157.

引证文献6

二级引证文献42

中华神经科杂志
2009年 第11期

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