1Yokota T,Sugawara K, ho K, et al. Down regulation of DJ - 1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition[J]. Neurochem,2005,94 : 1685.
2Rogaev E,Johnson J, Lang AE, et al. Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease[J]. Arch Neuro, 2004,61 (12) : 1898 - 1904.
3Valente EM,Abou-Sleiman PM,Caputo V,et al. Hereditary earlyonset Parkinson's disease caused by mutations in PINK1 [J]. Science, 2004,304 : 1158.
4Chu CT, Zhu JH,Cao G, et al. Apoptosis inducing factor mediatese caspase-independcnt 1 - methyl - 4 - phenylpyridinium toxicity in dopaminergic cells[J]. Biochem Biophys Res Commun,2003,312: 1342.
5Ono K, Hasegawa K, Naiki H, et al. Anti-parkinsonianagent : have anti-amyloido genieaetivity for Alzheimer, 5beta-amyloidfibrils in vitro[J]. Neurochem Int,2006,48:275.
6Nagatsu T, Currpharm, Sawada M, et al. Inflammatory process in Parkinson's disease:rolefor cytokines[J].Curr Pharm Des,2005 11:999- 1016.
7Nishioka K,Hayashi S,Farrer MJ,et al. Clinical heterogeneity of alpha-synuelein gene duplication in Parkinson's disease[J]. Neurol, 2006,59 : 298 - 309.
9Kruger R, Kuhn W, Muller T, et al. Ala30 promutation in the gene encoding α - synuclein in Parkinson' s disease[ J ]. Nat Genet, 1998, 18:106 - 108.
10Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the al-pha-synuclein gene identified in families with Parkinson' s disease [J ]. Science, 1997,276(5321 ) :2045 - 2047.
3Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the alpha-synuclein gene identified in families with Parkinson' s disease. Science 1997; 276 (5321 ):2045 - 7.
4Kruger R, Kuhn W, Muller T, et al. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson' s disease. Nat G enet 1998; 18 (2): 106 -8.
5Spillantini MC, Crowther RA, Jakes R, et al. alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson' s disease and dementia with lewy bodies. Proc Natl Acad Sci USA 1998; 95 ( 11 ): 6469 - 73.
6Yu S, Zuo X, Li Y, et al. Inhibition of tyrosine hydroxylase expression in a-synuclein-transfected dopaminergic neuronal cells. Neurosci Lett 2004; 367(1):34-9.
7Perez RG, Waymire JC, Lin E, et al. A role for alpha-synuclein in the regulation of dopamine biosynthesis.J Neurosci 2002:22 (8 ): 3090 -9.
8Richtand NM, Inagami T, Kuczenski R, et al. Purification and characterization of rat striatal tyrosine hydroxylase. Comparison of the activation by cyclic AMP-dependent phosphorylation and by other effectors. J Biol Chem 1985; 260(14): 8456 -73.
9Lindgren N, Xu ZQ, Lindskog M, et al. Regulation of tyrosine hydroxylase activity and phosphorylation at Ser(19) and Ser(40) via activation of glutamate N MDA receptors in rat striatum. J Neurochem 2000; 74(6): 2470 - 7.
10Isidoro A, Martinez M, Fernandez PL, et al. Alteration of the bioenergetic phenotvpe of mitochondrial is a hallmark of breast' gastric, lung and oesophageal cancer [J]. Bioehem J, 2004, 378 (Pt1): 17 - 20.
