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以颅神经麻痹、CT和MRI作为诊断鼻咽癌局部复发的研究 被引量:4

Cranidal nerve palsy and CT,MRI as diagnostic methods for local recurrence of nasopharyngeal carcinoma
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摘要 目的:进一步探索以颅神经麻痹(CNP)以及用CT和MRI诊断鼻咽癌局部复发(NPCLR)的方法。方法:选取100例超腔的NPCLR病人仔细研究其CNP的规律,及其CT和/或MRI的表现。结果:70%的NPCLR病人有CNP,主要侵犯外展神经(51.4%)和三叉神经(67.1%)。与此相反,颅神经放射损伤,则最多侵及舌下神经(67.4%)。在本组病人的CT和/或MRI片上均可见鼻咽以外的深部解剖结构受累的现象,其中最常受累者为颅底骨(58%),其次为海绵窦(25%),翼腭窝(21%),脑桥小脑角(16%),咽旁(14%)和鼻腔(12%),咽后淋巴结复发亦不少(22%)。结论:NPC放疗后出现CNP固然可以高度怀疑其局部复发,但最后诊断尚须根据CT,尤其MRI检查。 Objective:To explore further the cranial never palsy and CT, MRI for diagnosis of local recurrence of nasopharyngeal carinoma (NPCLR).Methods:By reviewing all available materials of 100 patients with confirmed NPCLR beyond the incolvemenr of nasopharynx.Results:Seventy patients had cranial nerve palysy mainly involved the abducent nerve (51.4%) and the trigeminal nerve (67.1%),in contrast to radiation induced injury which invdved mostly the sublingual nerve (67.4%).CT and MRI showed abnormal ities ities in deep structures which were as follows:base of skull (48%),cavernous sinus (25%),pterygopalatine fossa (21%),cerebellopontine angle (16%),parapharyngeal space (14%),nasal cavity (12%),and the Rouviere's nodes (22%).Conclusion:In view of development of cranial nerve palsy in patient after irradiation for NPC,NPCLR may be suspected,but the final diagnosis must be based upon CT and in particodar,the MRI findings.
作者 魏宝清
机构地区 江苏省肿瘤医院
出处 《上海医学》 CAS CSCD 北大核心 1998年第10期570-573,共4页 Shanghai Medical Journal
关键词 鼻咽肿瘤 局部复发 诊断 CT NMR 颅神经麻痹 Nasopharyngeal carcinoma Local recurrence CT MRI Cranial nerve palsy
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参考文献6

  • 1魏宝清,中国肿瘤,1997年,6卷,6页
  • 2魏宝清,中华放射肿瘤学杂志,1996年,5卷,164页
  • 3魏宝清,中华放射肿瘤学杂志,1996年,5卷,77页
  • 4魏宝清,浙江肿瘤,1995年,1卷,201页
  • 5魏宝清,中华放射肿瘤学杂志,1994年,3卷,164页
  • 6魏宝清,中华医学杂志,1986年,66卷,605页

同被引文献25

  • 1张有望,吴永如.鼻咽癌放疗后CT图象的变化[J].中华放射肿瘤学杂志,1992(4):11-16. 被引量:17
  • 2卢泰祥,李家尧,胡永红,张恩罴.鼻咽癌颅底骨破坏的临床研究[J].中华耳鼻咽喉科杂志,1994,29(5):295-298. 被引量:24
  • 3孟利,龙洁.动眼、滑车、外展神经麻痹62例病因分析[J].中国实用内科杂志,1996,16(6):359-361. 被引量:5
  • 4孔琳,张有望,吴永如,郭小毛.鼻咽癌放疗后长期生存者晚期副反应研究[J].中华放射肿瘤学杂志,2006,15(3):153-156. 被引量:72
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  • 6Thomke F.Isolated cranial nerve palsies due to brainstem lesions.Muscle Nerve,1999,22(9):1168~76.
  • 7Lee MS,Gelatta SL,Volpe NJ.et al. Six nerve palsies in children .Pediatr Neurol,1999 ,20(1):49~52.
  • 8Bedwinek JM,Perez CA,Key DJ. Analysis of failures after definitive irradiation for epidermoid carcinoma of the nasopharynx[J].Cancer,1 980,45(11):2725-2729.
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