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脑干胶质瘤的病理、临床与预后 被引量:1

Clinical and Pathologic Features of Brainstem Gliomas Associated with Outcome:54 Cases Report
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摘要 目的探讨病理形态学及其他因素对脑干胶质瘤预后判断的意义。方法对54例脑干胶质瘤患者进行回顾性分析及随访。结果和结论41例获得随访,首发症状为声音嘶哑、饮水呛咳或头晕;肿瘤级别高,形态学显示有坏死、核分裂象多、血管内皮增生以及Ki-67增殖指数>5%与生存率低有关,Rosenthal纤维多出现在低级别胶质瘤中,与较高生存率有关。 Objective To scan significant clinicopathologic parameters in brainstem giiomas (BG) for outcome. Methods 54 cases with BG were reviewed and followed up. Results and Conclusion 41 cases were followed up. The main complaint included hoarseness and bucking, dizziness. The higher tumor grade, higher mitotic-index, necrosis of tumor, hyperplasy of blood vessel endothelium, Ki-67 index 〉 5 % were associated with shorter survival. In opposite, Rosenthal fibers always presented in lower grade gliomas and associated with long survival.
出处 《中国康复理论与实践》 CSCD 2009年第11期1071-1073,共3页 Chinese Journal of Rehabilitation Theory and Practice
关键词 胶质瘤 脑干 预后 病理 KI-67 gliomas brainstem outcome pathology Ki-67
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参考文献15

  • 1Fisher PG, Carson BS. Management of brainstem glioma in children [J].Contemp Neurosurg, 1996,18:1--7.
  • 2Donaldson SS, Laninghan F, Fisher PG. Advances toward an unerstanding of brainstem gliomas[J]. J Clin Oncol, 2006, 24:1266-- 1272.
  • 3David NL, Hiroko O, Otmar DW, et al. The 2007 WHO classification of tumours of the central nervous system [J]. Acta Neuropathol, 2007, 114:97--109.
  • 4王忠诚,张俊廷,刘阿力.311例脑干胶质瘤的临床特征与手术治疗[J].中国医学科学院学报,2005,27(1):7-12. 被引量:34
  • 5Guillamo JS, Monjour A, Tailtandier L. Brainstem gliomas in a dults: prognostic factors and classification [J]. Brain, 2001, 124 : 2528--2539.
  • 6Badhe PB, Chauhan PP, Mehta NK. Brainstem gliomas -- a clinieo pathological study of 45 cases with p53 immunohistochemistry[J]. Indian J Cancer, 2004,41(4) :170-- 174.
  • 7Fisher PG, Breiter SN, Carson BS. A clinicopathologic reappraisal of brain stern tumor classification. Identification of pilocystic astrocytorna and fibrillary astrocytorna as distinct entities[J].Cancer, 2000,89(7) : 1569-- 1576.
  • 8Berger MS, Edwards MS, LaMasters D. Pediatric brain stem tumors: radiographic, pathological, and clinical correlations [J]. Neurosurgery, 1983,12(3) :298--302.
  • 9Kaplan AM, Albright AL, Zimmerman RA, et al. Brainstem glio mas in children: a Children's Cancer Group review of 119 cases[J]. Pediatr Neurosurg, 1996, 24 : 185-- 192.
  • 10Mauffrey C. Paediatric brainstem gliomas: Prognostic factors and management. (Clinical study) [J]. J Clin Neurosci, 2006,13 : 431 -- 437.

二级参考文献18

  • 1Yoshimura J, Onda K, Tanaka R, et al. Clinicopathological study of diffuse type brainstem gliomas: analysis of 40 autopsy cases. Neurol Med Chir (Tokyo), 2003, 43(8):375-382.
  • 2Epstein FJ, Farmer JP. Brain-stem glioma growth pattern.J Neurosurg, 1993, 78:408-412.
  • 3Constantini S, Epstein F. Surgical indication and technical considerations in the management of benign brain stem gliomas. J Neurooncol, 1996, 28:193-205.
  • 4Jallo GI, Biser-Rohrbaugh A, Freed D. Brainstem gliomas.Childs Nerv Syst, 2004, 20(3):143-153.
  • 5Lesniak MS, Klem JM, Weingart J, et al. Surgical outcome following resection of contrast-enhanced pediatric brainstem gliomas. Pediatr Neurosurg, 2003, 39(6):314-322.
  • 6Guillamo JS, Monjour A, Taillandier L, et al. Brainstem gliomas in adults: prognostic factors arid classification. Brain,2001, 124(Pt 12):2528-2539.
  • 7Yeh DD, Warnick RE, Ernst RJ. Management strategy for adult patients with dorsal midbrain gliomas. Neurosurgery,2002, 50(4):735-738.
  • 8Pollack IF, Hoffman HJ, Humphreys RP, et al. The long term outcome after surgical treatment of dorsally exophytic brain stem gliomas. J Neurosurg, 1993, 78(6):859-863.
  • 9Farmer JP, Monies JL, Freeman CR, et al. Brainstem Gliomas. A 10-year institutional review. Pediatr Neurosurg,2001, 34(4):206-214.
  • 10Wang CC, Zhang JT, Liu AL, et al. Surgical treatment of primary midbrain gliomas. Surg Neurol, 2003, 53:41-551.

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