摘要
目的:观察替罗非班对冠状动脉介入无复流现象的治疗效果。方法:对冠状动脉介入术中出现无复流现象39例患者依次给予硝酸甘油、维拉帕米和替罗非班,观察靶血管前向血流的TIMI分级。结果:替罗非班明显改善TIMI血流,治疗无复流现象的有效率(28/33)明显优于硝酸甘油的有效率(4/39)和维拉帕米的有效率(2/35),差异有统计学意义(P<0.01)。结论:替罗非班对冠状动脉介入术中无复流现象有确切疗效。
Objective： To observe the clinical effect of platelet GP Ⅱ b /Ⅲa receptor antagonist, Tirofiban in patients with no reflow during percutaneous coronary intervention （PCI）procedure. Methods： Thirty nine cases of no reflow patients during PCI procedure were infused with nitroglycerin, verapamil and Tirofiban by turns,and the target vessel TIMI flow was graded accordingly. Results： Tirofiban improved target vessel TIMI flow significantly than nitroglycerin and verapamil. Their effective percentage were 28/33,4/39,2/35, respectively. The differences were statistically significant（P〈0. 01 ）. Conclusions：Tirofiban has definite effect in patients with no reflow during PCI procure.
出处
《中国冶金工业医学杂志》
2009年第6期627-628,共2页
Chinese Medical Journal of Metallurgical industry
关键词
替罗非班
冠状动脉介入治疗
无复流现象
疗效
Tirofiban
Percutaneous coronary intervention
No reflow phenomenon
Effect
