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老年男性Ⅱ型糖尿病患者血清性激素变化及与冠心病的关系 被引量:2

Changes of serum sex hormone contents in elderly Type Ⅱ diabetic male patients with and without coronary heart disease
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摘要 对≥60岁的男性Ⅱ型糖尿病(Ⅱ-DM)患者及合并冠心病患者各50例进行研究,测定其血清T、E2、血糖(GLU)、TC、TG水平。结果:男性Ⅱ-DM及合并冠心病患者血清T低于健康对照组(P<0.05和P<0.01),血清E2也有下降趋势(P>0.05),E2/T比值则高于对照组(P>0.05);相关分析显示T与GLU、TC、TG均呈负相关(P<0.01),而E2则似乎与GLU、TC、TG无明显相关性,GLU与TC、TG呈正相关(P<0.01)。结论:Ⅱ-DM及冠心病患者均存在性激素改变,并与血糖、血酯一起构成影响糖尿病、冠心病的不利因素。 Serum levels of testosterone(T), estradiol(E 2),glucose(GLU), total cholesterrot(TC) and triglyceride(TG) were studied in 100 old non insuline dependent diabetes mellitus(NIDDM) male patients in which 50 cases complicated with coronary heart disease(CHD). The NIDDM patients with or without CHD had lower concentration of T and E 2 than that of the controls(P<0 05 and P<0 01).The concentration of E 2 were also lower in patients than that in the controls(P>0 05). The E 2/T ratio were relatively higher(P>0 05).The T level were negatively correlated with the levels of Glu, TC and TG, respectively. E 2 level did not correlated with Glu, TC, TG. But Glu was significantly correlated with TC and TG(P<0 01). The results indicated that there were changes of serum sex hormones, Glu, TC and TG in the patients suffer from NIDDM and CHD, with detrimental influence.
出处 《中国老年学杂志》 CAS CSCD 北大核心 1998年第5期272-273,共2页 Chinese Journal of Gerontology
基金 日本福岗财团提供赞助
关键词 糖尿病 性激素 冠心病 老年人 男性 NIDDM CHD Sex hormone Blood lipid
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参考文献4

  • 1张万年,卢兴,杨继声,张阿曼,李俱贤,王明新.男性心肌梗塞病人血清性激素的变化及其意义[J].西安医科大学学报,1991,12(1):30-32. 被引量:2
  • 2钟光恕,中华内分泌代谢杂志,1987年,3卷,2期,96页
  • 3邱鸿鑫,中华内分泌代谢杂志,1986年,2卷,2期,98页
  • 4陈名道,中华内科杂志,1982年,21卷,2期,67页

二级参考文献2

  • 1张阿曼,王明新,李俱贤,陈仲仲,张伯民,张万年,邹丽容.睾酮对男性急性心肌梗塞患者心泵功能的影响[J]陕西医学杂志,1988(12).
  • 2张万年,谭筱林,卢兴,杨继声,邹丽容.血浆性激素对心肌梗塞大鼠左室功能影响的实验研究[J]中国病理生理杂志,1987(03).

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