摘要
目的对滋阴清热法治疗咳嗽变异性哮喘的临床疗效进行评价。方法将68例咳嗽变异性哮喘患者随机分为两组,治疗组服用滋阴清热饮,对照组服用茶碱缓释胶囊;两组疗程均为4周。观察患者症状、气道反应性等变化。结果治疗组总有效率高于对照组;两组患者治疗后咳嗽、咽痒、咯痰等症状均有明显改善,而治疗组改善优于对照组;两组疗效及症状积分差异显著。两组治疗后最低反应阈值(Dmin)均升高,传导率下降斜率(sGrs)均下降,治疗组与对照组比较差异显著。3个月后随访治疗组复发6例,对照组复发14例,差异显著。结论滋阴清热法治疗CVA具有良好的临床疗效,其作用机制可能是通过抗气道变应性炎症,降低气道高反应性而实现,且远期疗效优于对照组。
Objective： To evaluate the effect of nourishing yin and cleating heat method on cough variant asthma （CVA） . Methods： 68 cases of CVA were divided randomly into two groups. The treatment group was used nourishing yin and clearing heat decoction. The control group was given theopylline sustained release capsules. After 4 weeks, the symptoms and the airway responsiveness of these patients were investigated. Results： The total effective rate of the treatment group was higher than that of the control group. There were obvious improvements in cough, itching throat, expectoration and some other symptoms in two groups. But these ameliorations in treatment group were superior to that in control group. There were significant differences of therapeutic effects and symptoms scoring in two groups. The Dmin was obviously increased and sGrs decreased in both groups, but there was obvious difference be- tween treatment group and control group. After 3 months, 6 relapse cases in treatment group were remarkable lower than 14 cases in control group. Conclusion： Method of nourishing yin and clearing heat possesses a good clinical effect for CVA. It may be decreasing bronchial hyperesponsiness by anti-inflammatory in allergic airway. Moreover, the treatment group is better than the control group in long-term effect.
出处
《中国中医急症》
2009年第12期1956-1958,共3页
Journal of Emergency in Traditional Chinese Medicine
关键词
咳嗽变异性哮喘
滋阴清热法
气道变应性炎症
气道高反应性
Cough variant asthma
Method of nourishing yin and cleating heat
Airway allergic inflammation
Bronchial hyperesponsiness
