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他汀类药物临床应用及不良反应 被引量:5

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摘要 他汀类药物的应用,是心血管疾病治疗的重大进展,具有显著的社会效益和经济效益。此类药物除调血脂和防治心血管病外,还具有改善内皮功能、抗血小板聚集、减轻或消除炎症反应及抑制动脉粥样硬化等众多作用。循证医学表明,他汀类药物可显著降低冠心病事件的发生率和死亡率。该类药物在国外的上市品种达20余个,国内主要有普伐他汀(Pravastatin)、洛伐他汀(Lovastatin)、辛伐他汀(Simvastatin),氟伐他汀(Fluvastatin)、阿托伐他汀(Atorvastatin)、美伐他汀(Mevastatin)等品种。本文结合有关文献,就其应用现状进行综述。
作者 靳凤霞
出处 《今日药学》 CAS 2009年第11期17-20,共4页 Pharmacy Today
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参考文献25

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二级参考文献76

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