摘要
目的:探讨妊娠合并甲状腺功能减退症对妊娠结局及胎儿的影响。方法:回顾性分析40例妊娠合并甲状腺功能减退症的患者资料,采用放免法测定其血清促甲状腺激素(TSH)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)浓度及其对妊娠结局和胎儿的影响。结果:妊娠合并甲状腺功能减退症孕妇的流产率、早产率、并发症发生率及新生儿TSH升高明显高于对照组(P<0.05),新生儿出生后1minApgar评分低于正常对照组(P<0.05)。结论:对妊娠合并甲状腺功能减退症的孕妇应定期监测血清FT3、FT4、TSH浓度,及时调整用药剂量,并密切关注各类并发症的出现,以减少不良妊娠结局的发生;对其新生儿建议取脐带血监测血清FT3、FT4、TSH浓度,以及时发现新生儿甲状腺功能减退症,并及时治疗。
Objective： To explore the effects of hypothyroidism during pregnancy on pregnant women and fetus. Methods： Clinical data of 40 pregnant women with hypothyroidism were analysed retrospectively, then serum levels of thyroid - stimulating hormone （TSH）, free triiodothyronine （FT3） and free thyroxine （FT4） were detected by radioimmunoassay. Results： The incidences of abortion, premature delivery and complications of pregnant women and TSH level of neonatal infants in hypothyroidism group were significantly higher than those in control group （ P 〈 0. 05 ） . The 1 minute Apgar score of neonatal infants in hypothyroidism group was significantly higher than that in control group （ P 〈 0. 05） . Conclusion： The serum levels of FT3, FT4 and TSH in pregnant women with hypothyroidism should b6 monitoreit throughout gestation, so as to find hypothyroidism of neonatal infants early and offer timely treatment.
出处
《中国妇幼保健》
CAS
北大核心
2009年第35期4982-4984,共3页
Maternal and Child Health Care of China
