摘要
ig肝胆结石片1.5、3.0（生药）／kg，无论致炎前或致炎后给药，均能显著降低二甲苯致小鼠耳肿胀率分别为68.4％、72.4％或42.2％、65.6％;对角叉菜胶致急性炎症有不同程度的抑制，对琼脂肉芽的抑制率分别为12.6％、24.1％;对毛细血管通透性增加的抑制率分别为320％、45.3％。表明肝胆结石片有良好的抗炎作用，且能提高胆道感染狗的胆汁中总胆汁酸、固形物及体重，提示本品有一定的抗感染作用。
Gandan Jieshe tablets(GJ) were orally given in dose of 1.5gm/kg or 3.0gm/kg either before or after induction of inflammation.The results showed that GJ could display the following effects:(1)decreasing xylene-induced ear edema in mice by 68.4%. 72.4% and 42.2%. 65.6% respectively;(2)inhibiting carrageenin-induced acute inflammation in more or less degree;(3)inhibiting agar-induced sub-chronic inflammation by 12.6% and 24.1 % respectively;(4)lowering the increase of capillary permeability by 32.0% and 45.3% respectively.It showed that GJ had satisfactory anti-inflammatory effect.In addition,GJ could raise the content of bile acid,solid substances in bile and body weight in dogs,which showed that GJ had considerable anti-infection effect.
出处
《中国药房》
CAS
CSCD
1998年第5期207-208,共2页
China Pharmacy
