摘要
目的探讨老年类风湿关节炎(RA)的临床特点。方法对47例年龄≥60岁的老年RA(ERA)及55例非老年RA(NERA)患者的临床症状和常用实验室检查等项目进行对比分析。结果与NERA组相比,ERA组起病较急,男性患病比例较高,具有较高的病情活动度;类风湿因子(RF)阳性率较低;抗环瓜氨酸多肽(CCP)抗体阳性率较高(P<0.01)。抗角蛋白抗体(AKA)阳性与病情活动程度有关。关节外表现以肺间质病变及心理因素异常多见。结论ERA患者早期诊断、早期治疗有利于阻止病情恶化发展。
Objective To study the clinical characteristics of elderly patients with rheumatoid arthritis （RA）. Methods Forty seven cases in age range ≥60 - year - old suffered from RA（ERA） and 55 cases of non - elderly RA（NERA） were studied, their clinical symptoms and results of laboratory examinations commonly used for such disease were analyzed. Results In comparison with NERA group, the onset of disease in patients of ERA group was more acute than that of NERA, it had a higher proportion of male prevalence, higher degree of disease activity and lower positive rate of rheumatoid factor （ RF）, and positive AKA was related to the degree of disease activity. Their positive rate of anti - CCP antibody was higher than that of patients with NERA group, their difference was statistically significant （ P 〈0.01 ）. The commonly seen extra - joint manifestations were interstitial lung disease and psychological factors. Conclusion Early diagnosis and treatment of ERA is favor for the prevention of deterioration of this disease.
出处
《临床和实验医学杂志》
2009年第12期30-31,共2页
Journal of Clinical and Experimental Medicine
关键词
类风湿关节炎
老年病学
临床特点
Rheumatoid arthritis
Geriatrics
Clinical features
