摘要
目的观察康艾注射液在晚期非小细胞肺癌综合治疗中的作用。方法将56例晚期非小细胞肺癌患者随机分为治疗组和对照组。治疗组(28例)用康艾注射液加化疗,并与单纯化疗组(28例)进行对照。结果治疗组有效率为35.7%(10/28),对照组有效率为32.1%(9/28),治疗组有效率略有提高,但差异无统计学意义(P>0.05);治疗组临床获益率60.7%(17/28);对照组临床获益率46.4%(13/28),差异有统计学意义(P<0.05);治疗组在骨髓抑制、消化道反应发生率方面均低于对照组(P<0.05);生活质量(KPS)评分改善治疗组高于对照组(P<0.05)。结论康艾注射液联合TP方案治疗晚期非小细胞肺癌有提高临床获益率,减轻毒性反应,提高生活质量的作用。
Objective To observe the effect of Kang＇ai injection on patients with advanced non-small cell lung cancer （NSCLC）. Methods Fifty-eight patients with advanced non-small cell lung cancer were randomly divided into two groups： treatment group （n=28） received Kang＇ai injection and chemotherapy, and control group （n=28） only accepted chemotherapy. Results The effective rate in the treament and the control group was 35.7%（10/28） and 32.t%（9/28） respectively, with insignificant difference between the two groups（P〉0.05）.The clinical benefit rate in the treament and the control group was 60.7% （17/28） and 46.4%（13/28） respectively,with significant difference between the two groups（P〈0.05）. The marrow suppression and gastrointestinal reactions in the treament group were all lower than those in the control group with significance （P〈O.OS）,and the improvement in Karnofsky scores in the former was higher than that in the control group （P〈0.05）. Conclusion In treatment of patients with advanced NSCLC,Kang＇ai injection with chemotherapy can improve the effect and reduce the toxocities,improve the live quality.
出处
《中国现代医药杂志》
2009年第12期12-13,共2页
Modern Medicine Journal of China
关键词
非小细胞肺癌
康艾注射液
化疗
Non-small lung cancer Kang＇ai injection Chemotherapy
