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胃癌术后调强放疗联合同期化疗的初步分析

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摘要 目的评价胃癌患者术后同期放化疗的近期疗效和毒性反应。方法32例胃癌术后患者采用调强放疗,靶区包括瘤床和区域淋巴引流区,同步化疗采用口服卡培他滨或多西他赛。放化疗后辅助化疗以Folfox方案为主,4~6疗程。观察疗效及毒性反应。结果全组1a总生存率、无复发生存率和局部区域控制率分别为87.5%、81.2%和93.7%。有2例中止同步放化疗,1例出现3度骨髓抑制,1例出血。白细胞下降发生率31%,3级占3%;胃肠道反应发生率46%,3级占3%。结论胃癌术后患者同期放化疗能提高局部控制率,且毒性反应是可耐受的。
出处 《山东医药》 CAS 北大核心 2009年第48期47-48,共2页 Shandong Medical Journal
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