摘要
目的探讨采用血液灌流（HP）联合连续性静脉——静脉血液滤过（CVVH）在急性重症中毒抢救中的临床价值．方法选择我院2007年8月～2009年9月急诊收治的28例重症中毒患者．在常规内科治疗基础上，采用HP联合CVVH治疗，对患者治疗前后的凝血指标、肝肾功能、血清酶学、氧合等指标的变化进行对照研究．结果治疗后患者的凝血指标、肝肾功能、血清酶学等指标较治疗前均明显降低（P〈0．05），生命体征明显改善；血小板较治疗前下降，但无出血现象．结论HP联合CVVH对急性重症中毒的救治具有重要作用，可短时间内清除体内的毒（药）物，明显改善患者的中毒症状、肝肾功能、血清酶学及凝血指标．稳定机体的内环境．有利于改善中毒患者的预后．
Objective To investigate the effect of combination of hemoperfusion with continuous veno-venous hemofiltration in rescuing patients with acute severe poisoning. Methods We have choised 28 patients, admitted by emmergency department from 2007-8 to 2009-9 for treatment of acute severe poisoning. In the base of routine medical treatment we adopted HP＋CVVH trerapy. A contrast analysis was carried out on indexes of blood coagulation, liver function, renal function, serum enzymology and oxygenation before and after therapy. Results After treatment there was an explicit decrease in indexes of blood coagulation, liver function, renal function and serum enzymology（P〈0.05）, and vital signs improved remarkably; platelet was decreased slightly, but the bleeding wasn＇t happen. Conclusion HP＋CVVH plays an important role in rescuing patients with acute severe poisoning; it can eliminate the poison（drug） in the short time and improve markedly toxic symptoms, liver and renal function and indexes of serum enzymology and coagulation, and it can stabilize inner environment of organism to be favorable to improve prognosis of patients.
出处
《蛇志》
2009年第4期273-275,共3页
Journal of Snake
关键词
血液灌流
血液滤过
中毒
Hemoperfusion
Hemofihration
Poisoning
