摘要
ＳＤ大鼠４０只，喂基础饲料预试验观察１周后，随机分为阴性对照组（ＮＧ）、高脂对照组（ＨＦ）、牛磺酸（ＴＡ）组、鸡冠花提取物（ＥＣ）组，每组１０只。ＮＧ组喂基础饲料，其余各组均喂高脂饲料，连续８周；ＴＡ组每日灌胃ＴＡ１００ｍｇ／ｋｇ，ＥＣ组。每日灌胃ＥＣ１００ｍｇ／ｋｇ。结果表明，牛磺酸和鸡冠花提取物不仅能显著增加高脂大鼠红细胞ＳＯＤ水平，降低动脉壁ＴＣ、ＭＤＥ及血清ＬＤＨ含量（Ｐ＜０．０５或Ｐ＜０．０１），而且可显著提高血清锌含量（Ｐ＜０．０５），同时鸡冠花可提高高脂大鼠血清铜含量（Ｐ＜０．０１）。牛磺酸和鸡冠花显著地降低了高脂大鼠的血清铜／锌比值（Ｐ＜０．０１），并有降低血清钙的作用。提示牛磺酸和鸡冠花可能通过调节体内的锌、铜、钙水平。
In order to evaluate the therapeutic effects of Selenium(Se) on Mycoplasma pneumonia, a clinical study was conducted in hospitalized patients using a double blind controlled method. The patients were randomly divided into two groups, the control patients received the routine treatment, and the supplemented group was given 1mg sodium selenite one time only in addition to the routine treatment. The present study showed that concomitant of Se and routine treatment was superior to routine treatment alone in terms of improvement of clinical signs, time needed for relieving symptoms and signs (P<005). The levels of Se and glutathione peroxidase in plasma and white blood cell were increased in Se supplemented group (P<005). Higher proportion of patients in the treated group showed normalization of T cell subset parameters as compared with the control group. It can be concluded that supplementation of Se would be conducive to the improvement of the nutritional status and the increase of the ability of resistinginfection.
出处
《卫生研究》
CAS
CSCD
北大核心
1998年第5期341-343,共3页
Journal of Hygiene Research
基金
河南省教委科研基金
关键词
牛磺酸
鸡冠花
锌
铜
钙
降血脂
selenium, mycoplasma pneumonia, mycocarditis
