摘要
目的探讨脑梗死(CI)患者血清可溶性血管黏附蛋白(sVAP)-1及C-反应蛋白(CRP)水平的变化。方法分别检测CI急性期患者(CI急性期组,20例)及恢复期患者(CI恢复期组,21例)血清sVAP-1、CRP水平,并与健康对照组(21人)比较。结果CI急性期组血清sVAP-1、CRP水平显著高于CI恢复期组及健康对照组(P<0.05～0.01);CI恢复期组血清CRP水平显著高于健康对照组(P<0.01);血清sVAP-1水平在两CI组间差异无统计学意义。CI急性期组血清sVAP-1与CRP水平呈正相关(r=0.841,P<0.001)。结论血清sVAP-1及CRP水平的变化可能与CI发生和发展有关。
Objective To observe the changes of the levels of serum soluble vascular adhesion protein（sVAP） - 1 and C-reactive protein（CRP） in patients with cerebral infarction（CI）. Methods The levels of serum sVAP-1 and CRP were detected in CI patients at acute stage （ACI group,20 cases） and at convalescence （CCI group,21 cases）. The results were compared with normal controls（ NC group, 21 cases）. Results The levels of serum sVAP-1 ,CRP in ACI group were significantly higher than those in CCI group and NC group（ all P 〈0.05 -0. 01 ）. The level of serum CRP in CCI group was significantly higher than this in NC group（ P 〈 0. 01 ） ; while the content of sVAP-1 was no obviously different between the two CI groups. There was positive correlation between the contents of sVAP-1 and CRP in the ACI group（ r = 0. 841, P 〈 0. 001 ）. Conclusion The changes of the levels of serum sVAP-1 and CRP may be related the occurrence and development of CI.
出处
《临床神经病学杂志》
CAS
北大核心
2009年第6期451-452,共2页
Journal of Clinical Neurology
关键词
可溶性血管黏附蛋白-1
C-反应蛋白
脑梗死
soluble vascular adhesion protein-1
C-reactive protein
cerebral infarction
