摘要
目的探讨妊娠期急性脂肪肝(AFLP)的临床特点,以便早期诊断和及时治疗。方法对近3年该院收治的10例妊娠期急性脂肪肝患者的临床资料进行回顾性分析。结果妊娠期急性脂肪肝为发生于妊娠晚期的一种严重并发症,主要症状有恶心、呕吐,黄疸,多数可并发妊娠期高血压综合征,严重病例短期内出现多脏器功能衰竭,所有入院诊断的孕产妇,均及时终止妊娠,死亡率为10%,围产儿死亡率30%,大多数病例在分娩后逐渐好转。结论早期诊断、尽快终止妊娠和血浆置换是提高母儿预后的关键;但即使早期终止妊娠,个别患者病情仍有可能进一步恶化,需引起临床警惕。
[ Objective ] To explore the clinical features of acute fatty liver of pregnancy （AFLP） for early diagnose and management timely. [Methods] The clinical findings and outcomes of pregnancy were analyzed in 10 patients with AFLP at our hospital in recent 3 years. [ Results ] Acute fatty liver of pregnancy is a serious syndrome occurs in terminal pregnancy. Nausea, vomiting, jaundice were the predominant symptoms, many cases can following pregnancy induced hypertension, and severe cases appear multiple organ failure. All pregnant women terminate pregnancy in time after diagnosis, The mortality of all maters were 10 percent, and the mortality of neonates were 30 percent. Most cases gradually improved after delivery.[ conclusion ] Making early diagnose, ending the pregnancy timely and plasma exchange are the key point to increase the prognosis of mater and neonate, but some cases may deteriorate even with early pregnancy termination and need more attentions.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2009年第18期2824-2827,共4页
China Journal of Modern Medicine
关键词
妊娠期急性脂肪肝
诊断
治疗
acute fatty liver of pregnancy
diagnosis
treatment
