摘要
目的评价哌拉西林/他唑巴坦在治疗尿道狭窄感染时的疗效和安全性。方法采用回顾性分析方法,病例均来自医院泌尿外科,其中126例应用哌拉西林/他唑巴坦治疗,24例应用头孢哌酮/舒巴坦治疗,根据卫生部新药临床研究指导原则标准判定疗效。结果应用哌拉西林/他唑巴坦和头孢哌酮/舒巴坦治疗尿道狭窄合并感染的临床有效率分别为88.89%和91.67%,细菌清除率为90.72%和93.75%;两种治疗方法相比,疗效差异无统计学意义(P>0.05)。结论哌拉西林/他唑巴坦治疗尿道狭窄合并感染疗效明显、安全性好。
OBJECTIVE To evaluate the effect and safety of piperacillin/tazobactam in the treatment of urethral stricture complicated with infection.METHODS All 150 patients with urethral stricture complicated with infection were divided into two groups treated with different antibiotics.The 126 cases were treated with piperacillin/tazobactam and the 24 cases were treated with cefperazone/sulbactam.RESULTS The clinical effective rates of piperacillin/tazobactam and cefperazone/sulbactam in treating urethral stricture complicated with infections were 88.89% and 91.67%,respectively.The bacterial eliminating rates was 90.72% and 93.75%,respectively.There was no significant difference between two groups（P〉0.05）.CONCLUSIONS Piperacillin/tazobactam in the treatment of urethral stricture complicated with infection is significantly effective and safely.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第23期3241-3243,共3页
Chinese Journal of Nosocomiology
