摘要
目的:用胜红蓟不同极性的提取物,筛选胜红蓟治疗慢性咽炎的活性部位。方法:依次用石油醚、乙酸乙酯、正丁醇和水提取胜红蓟,得到不同极性提取物,分别进行二甲苯诱导小鼠耳肿胀实验和用琼脂稀释法测定咽炎致病菌菌株的MIC值。结果:石油醚和正丁醇提取部位有对小鼠的耳肿胀有明显的抑制作用;不同提取物对咽炎致病菌抑菌作用差异较大。结论:石油醚和正丁醇部位有明显的抗炎作用,其抑菌作用可能不是胜红蓟治疗慢性咽炎的主要因素。
Objective： With different polar extraction of Ageratum conyzoide, Screening of Effective Parts in treatment of chronic pharyngitis from Ageratum conyzoide. Methods ：Ageratum Conyzoide was Extracted by the petroleum ether, the ethyl acetate, n - butanol and the water in sequence, obtains the different polar extraction, ear swelling experiment of mice induced by xylene and the minimum inhibition concentration measured were carried respectively. Results：extract parts of petroleum ether, n - butanol can significantly inhibit degree of ear swelling experiment of mice（ P 〈 0.05 ） , the bacteriostasis of different extractions were great difference. Conclusion： extract parts of petroleum ether, n -butanol have a obvious anti - inflammatory effect, but the bacteriostasis of Ageratum Conyzoide is not a main factor of treatment of chronic pharyngitis.
出处
《中华中医药学刊》
CAS
2010年第1期185-186,共2页
Chinese Archives of Traditional Chinese Medicine
关键词
胜红蓟
慢性咽炎
有效部位
筛选
Ageratum conyzoide
chronic pharyngitis
Effective Parts
