摘要
目的:调查某医院常见清洁手术围术期抗菌药物预防应用的情况,从而促进合理用药。方法:随机抽取2008年1～12月240例6类常见的清洁手术(白内障手术、乳腺手术、骨科手术、斜疝修补术、甲状腺手术及心脏手术)的病历,调查抗菌药物预防应用的情况。结果:240例患者抗菌药物预防性使用率100%;使用率最高的3类抗菌药物分别是第1代头孢菌素(43.48%),第3代头孢菌素(14.91%)和林可霉素类(8.08%);无针对性药物选择使用率高达75%;给药剂量及给药次数合理的比例分别是55%和40%;联合用药的比例是29.99%;仅仅43.33%的患者抗菌药物使用时机是在术前2小时内;抗菌药物平均使用时间是5.75天,抗菌药物使用时间最长者达12天。结论:该医院手术期抗菌药物预防应用不合理情况很普遍,应引起足够重视。
OBJECTIVE： To investigate the perioperative prophylactic use of antibiotics in patients with common aseptic operation in a hospital so as to promote rational drug use. METHODS： The medical records of 240 patients undergoing common operations such as cataract surgery, breast surgery, bone surgery, hemiorrhaphy, thyroid surgery or heart surgery in a hospital from January to December in 2008 were randomly selected for analysis of the perioperative prophylactic use of antibiotics. RESULTS： Prophylactic antibiotics were used in all 240 cases （100%）, leading the first 3 places were the first generation of cephalosporins （43.48%）, the third generation cephalosporins （ 14.91 % ） and lincomycins （8.08%）. 75% of the patients used antibiotics improperly. 55 % patients received antibiotics in rational dosage and 40% received antibiotics in rational medication frequency. 29.99 % received antibiotics in combination. Only 43.33 % of patients received antibiotics within 2h prior operation. The average duration of antibiotic use was 5.75 days, with the longest duration up to 12 days. CONCLUSION： Great importance should be attached to the widespread irrational use of prophylactic antibiotics.
出处
《中国医院用药评价与分析》
2009年第12期904-906,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
清洁手术
抗菌药物
预防性应用
Aseptic operation
Antibiotics
Prophylactic use
