摘要
肝脏缺血再灌注损伤(ischemia-reperfusion injury,I/R)是困扰肝脏外科发展的一大重症,如何防治I/R一直是研究的热点.预处理通过诱导细胞的内源性保护机制,对肝脏I/R有明显的防治作用,本文就各种预处理对抗肝脏I/R的作用机制作一综述,探讨各种预处理方法的临床应用价值.
Hepatic ischemia-reperfusion injury （I/R） is a major clinical problem that impedes the development of liver surgery. Recently, intensive research has improved our understanding of the mechanisms involved in I/R liver injury. Here, we will briefly review the most promising preconditioning approaches against I/R injury and discuss the mechanisms involved in their therapeutic effects.
出处
《世界华人消化杂志》
CAS
北大核心
2009年第33期3426-3430,共5页
World Chinese Journal of Digestology
基金
云南省自然科学基金资助项目
No2007C137M~~
关键词
预处理
防治
肝缺血
再灌注
损伤
Liver
Ischemia-reperfusion injury
Hepatic transplantation
Preconditioning
