摘要
目的:比较3种用药方案治疗重度痤疮的经济学效果。方法:126例门诊重度痤疮患者随机分成A、B、C组,分别给予异维A酸、米诺环素、炔雌醇环丙孕酮治疗,12周后观察疗效,并用最小成本分析法进行药物经济学评价。结果:A、B、C组总有效率分别为76.19%、73.91%、71.05%(P>0.05),成本分别为437.54、492.24、262.84元。结论:对有适应证的重度痤疮患者,炔雌醇环丙孕酮是最经济的治疗方案。
OBJECTIVE： To compare the pharmacoeconomic effectiveness among 3 therapeutic regimens for severe acne. METHODS： A total of 126 patients with severe acne were randomly divided into 3 groups to be treated with Isotretinoin （Group A）, Minocycline （Group B） or Ethinylestradiol cyproterone （Group C）. After treatment for 12 weeks, pharmacoeconomic evalua- tion was performed by using cost-minimization analysis. RESULTS： The total effective rates of the 3 groups （Group A, B and C） were 76.19%, 73.91%, 71.05%, respectively（P〉0.05）, and the costs were 437.54 yuan, 492.24 yuan and 262.84 yuan, respec2 tively. CONCLUSION： Ethinylestradiol cyproterone is the most economical therapeutic regimen for the indicated severe acne cases.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第2期100-102,共3页
China Pharmacy
基金
汕头市重点科技项目(汕府科[2008]85号)
关键词
重度痤疮
药物经济学
最小成本分析
Severe acne
Pharmacoeconomic
Cost-minimization analysis
