摘要
目的研究冠心病(CHD)患者血清尿酸(UA)、胆红素(BIL)和血浆纤维蛋白原(Fib)水平的变化,探讨其与CHD发生的关系。方法符合条件并经冠状动脉造影确诊的112例CHD患者为冠心病组,健康体检者150例为对照组,空腹抽血检测两组受试者的血清UA与总胆红素(TBIL)、直接胆红素(DBIL)及血浆Fib浓度,应用公式计算出间接胆红素(IBIL)浓度,并进行相关统计学分析。结果CHD组UA较对照组增高,差异有统计学意义(P<0.01);Fib与对照组相比较差异有统计学意义(P<0.05);TBIL、IBIL浓度较对照组明显降低,差异有统计学意义(P<0.01),DBIL变化不明显。结论血清UA、BIL及Fib与CHD的发生和发展关系密切,是导致CHD的危险因素。
Objective To observe the levels of uric acid（UA） ,bilirubin （BIL） and fibrinogen（Fib） to explore their relationships with coronary heart disease（CHD）. Methods The levels of UA,BIL and Fib among 112 patients with CHD and 150 normal persons were measured. Results The level of UA in the patients with CHD was higher than that in the control group. The difference was significant （P〈0.01）. The level of Fib between CHD patients and normal persons had statistically significant difference（P〈0.05）. The concentrations of TBll. and IBIL in the CHD group were lower compared with the control group （P〈0.01）. No significant change was detected on DBIL. Conclusion UA,BIL and Fib participate in the occurrence and development of CHD and they are the risk factors of CHD.
出处
《检验医学与临床》
CAS
2010年第2期134-135,共2页
Laboratory Medicine and Clinic
关键词
冠心病
尿酸
胆红素
纤维蛋白原
coronary heart disease
uric acid
bilirubin
fibrinogen
