摘要
对于顽固性高血压患者,无论是否伴有明显的血醛固酮增多,在监测血钾及药物不良反应的条件下,加用小剂量醛固酮拮抗剂可得到意想不到的降压效果以及保护靶器官的作用。现将通过近年多项相关临床试验,探讨醛固酮拮抗剂在顽固性高血压治疗中的地位。
For patients with refractory hypertension, the administration of low-dose aldosterone antagonists can facilitate significant, additional blood pressure reduction and protection of target organs independently of serum aldosterone levels. Based on a number of recent clinical trials this article will explore the role of aldosterone antagonists in the treatment of refractory hypertension .
出处
《心血管病学进展》
CAS
2010年第1期55-58,共4页
Advances in Cardiovascular Diseases
关键词
顽固性高血压
醛固酮
螺内酯
依普利酮
refractory hypertension
aldosterone
spironolactone
eplerenone
