摘要
目的探讨原发性输尿管肿瘤的诊断和治疗方法。方法对11例原发性输尿管癌患者的临床资料进行回顾性分析。全组均行患侧肾、输尿管全切除加膀胱袖口状切除术。术后2周给与GC(吉西他滨+卡铂)方案进行化疗,评价近期疗期疗效。结果本组通过B超、静脉尿路造影(IVU)、逆行肾盂造影、CT等检查,术前基本确诊。11例手术后病理诊断均为浸润性尿路上皮癌(移行细胞癌)。化疗完成1个周期6例,2个周期5例。近期疗效显著,随访未发现复发、远处转移及死亡的病例。结论对于原发性输尿管癌应当综合多种影像学检查方法以提高确诊率。肾、输尿管全长切除加膀胱袖口状切除术是治疗原发性输尿管癌的规范方法。对于局部进展期浸润性尿路上皮癌,术后辅助化疗可能提高患者的生存期和降低远处转移率。
Objective To improve the diagnosis and treatment of primary ureteral cancer. Methods Data of 11 cases of primary ureteral cancer were retrospectively analyzed. Ultra sound, IVU, cystoscopy, retrograde,ureteropyelography and CT were used to confirm the diagnosis before operation. Then radical nephroureterectomy with an ipsilateral bladder cuff resection was performed in each case, Two weeks after operation, carboplatin combined with chemotherapy （GC）was conducted and the results were evaluated. Results All 11 cases were confirmed to be advanced and invasive urothelial carcinoma. The overall response rate was notable in the near future. No death, palindromia or metastasis occurred. Conclusion The diagnostic accuracy rate of primary ureteral carcinoma may be improved by combination of various tests. The radical nephroureterectomy with an ipsilateral bladder cuff is effective for primary urecteral cancer. The GC chemotherapy may provide therapeutic benefit in the treatment of patients with partly advanced and invasive urothelial carcinoma of the primary urecteral cancer.
出处
《现代泌尿外科杂志》
CAS
2010年第1期20-21,共2页
Journal of Modern Urology
关键词
输尿管肿瘤
化疗
手术治疗
primary urecteral cancer
chemotherapy
operation
