摘要
我科自1983年7月～1996年7月共收治住院的ML病人88例，其中男性60例，女性28例，年龄0．5～80岁，中位年龄为42岁。何杰金病（HD）7例，非何杰金淋巴瘤（NHL）81例。与本校综合医院1992年以后同期收治的ML病人比较，颌面颈部ML病人占10．7％～23．6％。39例病人接受综合治疗，33例接受单纯化疗。随访病人存活时间超过7年者7例，超过5年者9例。存活病人中以临床Ⅰ、Ⅱ期者占绝大多数，而死亡病人中以Ⅲ、Ⅳ期居多。死亡病人平均存活23．6月（4～55个月），中位存活时间为12个月。研究结果提示：1．颁面颈部ML发病有明显增长趋势，应引起足够重视。2．对颌面颈部诊断不明的包块应不惜反复活检以确定诊断，特别是对T系ML。3．以化疗为主的综合治疗仍是有效的主要手段。4．临床分期对估计预后有重要的参考价值。
Malignant lymphoma (ML) is a general systemic disease. ML happened in oral and maxillofacial region israre, about 3% of whole body. There were 88 cases who were diagnosed as ML pathologically admitted in our department between July of 1983 and July of 1996. Among those patients, males were 60, females 28, the ageranged from 0. 5 to 80 years old, The middle age was 42-year-old. 7 cases were Hodgkin's disease (HD) and 81cases non-Hodgkin's lymphoma (NHL). When compared with ML in-patient in our general hospital between 1992and 1995, ML in maxilloface and neck were up to 10. 7 %～23. 6% in total. There were 39 cases accepted systemictreatment, 33 cases chemotherapy only. The total survival rate over 7 years was 8%, over 5 years 10. 2%. Amongsurvivals, most were Ⅰ and Ⅱ stage clinically, while in those had gone away, most belonged to Ⅲ and Ⅳ stageand their survival time was 23. 6 months in average (4 to 55 months), the middle survival time was 12 months.The results point out that there is an significantly increasing trend for incidence of ML in maxilloface and neckwhich should be paid much attention to. Repeated biopsy should be carried out if nuclear mass in maxilloface andneck exists, especially for T-cell ML. Chemotherapy combined with radiotherapy and operation is still the effectivetherapeutic means; The clinical staging classification is worth the prognosis.
出处
《口腔颌面外科杂志》
CAS
1998年第3期157-159,共3页
Journal of Oral and Maxillofacial Surgery
关键词
恶性
淋巴瘤
颌面颈部
诊断
治疗
Malignant lymphoma
Hodgkin's disease
Non-Hodgkin's
Lymphoma
