摘要
目的:了解我院药品不良反应(ADR)发生的特点。方法:对我院2008年8月1日～2009年5月30日收集的216例ADR报告分别从药品种类、年龄分布、给药途径、累及器官或系统及临床表现等方面进行统计分析。结果:216例ADR报告中,涉及药物以抗感染药居多(63.9%),其次为中药制剂;患者(≥60岁)ADR发生率最高(29.6%);静脉给药方式是引发ADR的重要给药途径(87.5%);ADR最为常见的临床表现为皮肤及附件损害(44.4%)。结论:引发药物ADR的原因很多,正确认识并展开全方位的监测,可以有效减少甚至避免ADR的发生。
Objective： To study the characteristics of adverse drug reactions （ADR） in our hospital. Methods： 216 ADR reports collected from Aug 1, 2008 to May 30, 2009 in our hospital were analyzed statistically in respect of drug categories, age distribution, routes of administration, organs or systems involved, and clinical manifestations. Results： Of the 216 ADR reports, 63.9% were induced by anti-infective drugs, followed by Chinese herbal medicine preparations; 29.6% occurred in patients aged not less than 60; 87.5% were induced through intravenous way; and damages of skin and its appendants were the most common manifestations, taking acount of 44.4%. Conclusion： There are a lot of reasons leading to ADR, awareness on ADR monitoring should be strengthened and the related report analysis system should be improved to reduce or avoid the occurrence of ADRs.
出处
《中国医药导报》
CAS
2010年第4期123-124,共2页
China Medical Herald
关键词
药品不良反应
抗感染药
中药制剂
Adverse drug reaction （ADR）
Anti-infective drugs
Chinese herbal medicine preparations
