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血清HE4测定在诊断卵巢恶性肿瘤中的价值 被引量：6

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摘要 目的探讨血清人附睾蛋白(human epididymis protein 4,HE4)和CA125联合测定对卵巢癌的诊断价值。方法采用酶联免疫法,分别对25例卵巢癌患者、22例良性卵巢肿瘤以及38例正常妇女血清HE4水平和CA125水平进行测定。结果卵巢癌患者血清HE4水平为(384.51±97.23)pmol/L,CA125水平为(2 109.08±937.67)U/L;良性卵巢肿瘤患者血清HE4水平为(48.18±16.98)pmol/L,CA125水平为(43.51±9.74)U/L;对照组HE4水平为(20.16±12.76)pmol/L,CA125水平为(18.35±6.82)U/L。3组比较差异有统计学意义(P<0.05),HE4与CA125联合诊断卵巢肿瘤敏感性为96%。结论血清HE4测定对卵巢癌诊断具有较高价值,与CA125联合检测可以提高诊断的敏感性,具有很好的推广价值。
作者 张海荣 商微 冀立娟 王蔼明
机构地区 中国人民解放军海军总医院妇产科
出处 《河北医科大学学报》 CAS 2010年第2期218-219,共2页 Journal of Hebei Medical University
关键词 卵巢肿瘤 酶联免疫吸附测定 附睾分泌蛋白类
分类号 R737.31 [医药卫生—肿瘤]
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二级参考文献8

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共引文献97

同被引文献76

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引证文献6

二级引证文献47

河北医科大学学报
2010年 第2期

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